What is Sermorelin acetate,how does it work?

Sermorelin acetate is one of the GHRH(growth hormone releasing hormone) analogues, which has the effect of promoting the release of GH(growth hormone), how does it work?

What is Sermorelin acetate?

There are two naturally occurring GHRH analogues: GHRH1-40)-OH and GHRH(1-44)-NH2. Sermorelin acetate are truncated GHRH analogues containing 1-29 amino acid fragments of human GHRH, which are considered to be the shortest fully functional fragment of GHRH. Therefore, it has a similar effect to GHRH. The FDA approved the peptide in 1997 for clinical use to treat age-related GH deficiency and promote growth in children.

Under natural conditions, Sermorelin acetate is a sterile, pyrogen free white freeze-dried powder that dissolve and administer by injection under the skin. It has a short half-life of about 11 minutes. However, unlike other peptides,  we don’t need to inject Sermorelin acetate frequently, only once a day.

How does Sermorelin acetate work?

Sermorelin acetate has a similar effect to GHRH in that it binds to the human GHRH receptor and stimulates the release of GH. Different from direct GH supplementation, Sermorelin acetate stimulated the natural and pulsing release of GH. The effect of this mode of action was similar to that of GHRH stimulated the pulsing release of GH. Therefore, the increase of GH level with Sermorelin acetate was more similar to the increase of natural HGH level in human body. Sermorelin acetate increases HGH levels by acting in a similar way to HGH naturally secreted by the body. By boosting natural HGH levels, Sermorelin acetate promotes muscle strengthening and helps burn fat, thereby altering the user’s body composition, leaving the user with more lean muscle and less fat.

Bodybuilders use peptides Sermorelin acetate because the effects of Sermorelin acetate were similar to those of cutting. In fact, in addition to the above main results, Sermorelin acetate will also increase the endurance level of bodybuilders, increase recovery, maintain bone health, etc.

As well as bodybuilders using Sermorelin acetate, some people are also using Sermorelin acetate to combat ageing. Sermorelin acetate is also known as an anti-aging peptide, and in fact HGH is also used in the field of anti-aging. HGH promotes cell proliferation, increases metabolic levels and protein synthesis, and provides the effect of slowing and reversing aging. The use of Sermorelin acetate can safely increase the HGH levels that decrease with age, without inhibiting their own HGH levels or causing the side effect of HGH overdose.